The effects of dietary omega-3 and omega-6 fatty acids glucose tolerance and pancreatic insulin concentration in C57BL/KSJ db/db mice

The effects of dietary omega-3 and omega-6 fatty acids glucose tolerance and pancreatic insulin concentration in C57BL/KSJ db/db mice Suraj, Rohini, "The effects of dietary omega-3 and omega-6 fatty acids glucose tolerance and pancreatic insulin concentration in C57BL/KSJ db/db mice" (1990). CUNY Academic Works. ACKNOWLEDGMENTS Special thanks to Dr. Ronald W. Schwizer for being my sponsor and for the use of his laboratory. His patience, encouragement and assistance was of immense help to me throughout this study. Thanks to the Baruch College Fund for providing necessary funds, and also to Dr. Norman Fainstein, Dean, School of Liberal Arts and Sciences, who provided the money to repair a vital piece of equipment necessary for this study. Thanks to Sean Pickering and Michael Dempsey for their assistance with laboratory work and animal care during this study. I would also like to thank Mr. Dalchand Rampaul, Senior College Laboratory Technician, for the use of his computer and office during the preparation of this paper. Fig. 1 Major metabolites of linoleic (omega-6) and linolenic (omega-3) fatty acids Fig. 2 Changes in body weight during 8 weeks of dietary supplementation and a) db/+ and b) db/db mice Fig. 3 Plasma glucose concentration during 8 weeks of dietary supplementation in a) db/+ and b) db/db mice Fig. 4 Pancreatic insulin concentration after 8 weeks of dietary supplementation in db/+ and db/db mice Fig. 5 The effects of 8 weeks of dietary supplementation on plasma glucose concentration during a 2-hour glucose tolerance test